RNA Details
Disease Name
idiopathic pulmonary fibrosis
Tissue
lung
RNA Symbol
Sox9
RNA ID
RNA Type
mRNA
Alteration Pattern
up regulation
Species
mus musculus
Detection Methods
Immunohistochemistry; Immunofluorescence; Western Blot etc.
Target
NA
Pathway
NA
PubMed ID
Title
Dysregulated overexpression of Sox9 induces fibroblast activation in pulmonary fibrosis
Year
2021
Function
We demonstrate that Sox9 is upregulated via MAPK/PI3K-dependent signaling and by the transcription factor Wilms' tumor 1 in distal lung-resident fibroblasts in IPF.